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MSD Announces Positive Study Investigating the Use of Pembrolizumab Compared to Chemotherapy in Patients with Ipilimumab-Refractory Advanced Melanoma
2014-11-16 10:25:00| Merck.com - Research & Development News
Dateline City: ZURICH Pembrolizumab Demonstrated Superiority to Chemotherapy for Primary Endpoint of Progression-Free Survival Findings Presented for First Time at Society of Melanoma Research (SMR) 2014 International Congress ZURICH--(BUSINESS WIRE)--MSD, known as Merck in the United States and Canada, announced today that a pre-specified analysis of investigational data from a pivotal Phase 2 study (KEYNOTE-002) showed pembrolizumab, the companys anti-PD-1 therapy, substantially improved the primary endpoint of progression-free survival (PFS, as assessed by RECIST 1.1, independent central review) (HR 0.57 and 0.50 for 2 mg/kg and 10 mg/kg every three week doses, respectively), compared to chemotherapy (P<0.0001 for both comparisons) in patients with ipilimumab- Language: English Contact: MSDMedia:Lainie Keller, +1-908-236-5036Claire Mulhearn, +1-908-236-1118orInvestor:Joseph Romanelli, +1-908-423-5185Justin Holko, +1-908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more
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Merck Announces Positive Study Investigating the Use of KEYTRUDA (pembrolizumab) Compared to Chemotherapy in Patients with Ipilimumab-Refractory Advanced Melanoma
2014-11-16 10:25:00| Merck.com - Research & Development News
Dateline City: ZURICH KEYTRUDA Demonstrated Superiority to Chemotherapy for Primary Endpoint of Progression-Free Survival Findings Presented for First Time at Society of Melanoma Research (SMR) 2014 International Congress ZURICH--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, announced today that a pre-specified analysis of investigational data from a pivotal Phase 2 study (KEYNOTE-002) showed KEYTRUDA (pembrolizumab), the companys anti-PD-1 therapy, substantially improved the primary endpoint of progression-free survival (PFS, as assessed by RECIST 1.1, independent central review) (HR 0.57 and 0.50 for 2 mg/kg and 10 mg/kg every three week doses, respectively), compared to chemotherapy (P<0.0001 for both comparisons) Language: English Contact: MerckMedia:Lainie Keller, 908-236-5036Claire Mulhearn, 908-236-1118orInvestor:Joseph Romanelli, 908-423-5185Justin Holko, 908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more
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Retail sales bounce back in October in positive sign for holiday season
2014-11-15 06:38:52| Grocery - Topix.net
An employee stocks bottles of wine at a Whole Foods Market in Dublin, Ohio, on Nov. 7. A 0.3% rise in retail sales last month after a September drop bodes well for a strong holiday shopping season Retail sales bounced back last month after a disappointing September drop, providing positive consumer-spending momentum heading into the holiday shopping season. Lower gasoline prices helped put consumers in the spending mood, said Jack Kleinhenz, chief economist at the National Retail Federation.
Industry takes positive step to sustainable fashion
2014-11-14 12:27:00| Daily apparel & textile news and comment - from just-style.com
Fashion designers, brands and suppliers including Stella McCartney, G-Star Raw, Bionic Yarn, Loomstate and Saitex have joined a new sustainability initiative aimed at helping businesses improve the way clothes are made and spurring the creation of more eco-friendly materials.
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Advanced Photonix, Inc. Reports Continued Revenue Growth And Positive EBITDA
2014-11-11 20:18:33| Semiconductors - Topix.net
Gross profit margin for Q2 FY2015 was 33.7% of sales compared to 37.0% for the second quarter ended . The lower gross profit percentage has been driven by the growing mix of 100G HSOR product sales at competitively priced levels and a decline in Terahertz revenue.
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