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Optimization Of Design Space And Throughput Conditions For Scale Up Of A Low- Dose Roller Compacted Product

2015-01-20 11:23:07| drugdiscoveryonline Downloads

Roller compaction of low dose active pharmaceutical ingredients into solid dosages forms is quite challenging.  Ribbon porosity, tensile strength, mean granule size and surface area are key quality attributes that can affect downstream processing and final product performance. These parameters were evaluated in the present study to establish a design space and operational conditions for roller compaction of a placebo tablet blend that closely mimics the formulation requirements of low dose pharmaceutical active ingredients. This study also helps to minimize the API need that often in limited supply during early stage of drug development.

Tags: conditions design product low

 

Design Optimization with XFdtd EM Simulation Software Using GPU Acceleration and Particle Swarm Optimization

2013-12-16 17:05:10| rfglobalnet Downloads

Devices designed for free space operation often fail to meet expectations when deployed in their actual environment. This study considers the example of designing a broadband antenna for an unattended ground sensor using Remcom's XFdtd Release 7 (XF7).

Tags: software design simulation optimization

 
 

Optical Design Software includes optimization algorithm.

2013-09-19 14:31:47| Industrial Newsroom - All News for Today

Streamlining design and analysis, CODE V® v10.6 includes Step Optimization feature, which uses algorithm to accelerate optimization convergence and navigate complicated solution spaces. STP can also speed up optimization when used with Reduce Tolerance Sensitivity feature to minimize impact of tolerances on system performance. With customizable 2D/3D charting features, users can rotate and zoom 3D charts, select Cartesian 2D or 3D surface charts, and interactively explore data points of interest. This story is related to the following:Vision SystemsSearch for suppliers of: Optical Design & Analysis Software

Tags: software design includes optical

 

Design and Optimization of a Board-to-Chip Transition

2013-02-20 10:28:50| rfglobalnet Downloads

AnalystTM is a 3D EM finite element method (FEM) simulator. This application note discusses the use of 3D electromagnetic simulators to help design board-to-chip transitions and highlights the features of Analyst by demonstrating the optimization of the transition from a board-to-chip signal path.

Tags: design transition optimization design optimization

 

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