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Merck and NanoString Announce Clinical Research Collaboration to Develop an Immune-Related Gene Expression Assay for Use in the Development Program for KEYTRUDA (pembrolizumab)

2015-05-28 14:30:00| Merck.com - Product News

Dateline City: KENILWORTH, N.J. & SEATTLE Collaboration Builds on Mercks R&D and NanoStrings Biomarker Development Leadership Positions in Immuno-Oncology Early Data Evaluating Immune-Related Signatures with KEYTRUDA in Multiple Cancers to be Presented for the First Time at 2015 ASCO Annual Meeting KENILWORTH, N.J. & SEATTLE--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, and NanoString Technologies, Inc. (NASDAQ:NSTG) today announced a clinical research collaboration to develop an assay that will optimize immune-related gene expression signatures and evaluate the potential to predict benefit from Mercks anti-PD-1 therapy, KEYTRUDA (pembrolizumab), in multiple tumor types. Language: English Contact: Merck Media Relations:Pamela Eisele, 267-305-3558Claire Mulhearn, 908-236-1118orMerck Investor Relations:Justin Holko, 908-740-1879orNanoString Investor/Media Relations:Leigh Salvo, 415-513-1281 Ticker Slug: Ticker: MRK Exchange: NYSE Ticker: NSTG Exchange: NASDAQ read more

Tags: for research development program

 

Respiratory Assay simultaneously detects 22 pathogens.

2015-04-17 14:31:07| Industrial Newsroom - All News for Today

With tube strip design accommodating throughput required to respond to seasonal changes in demand, NxTAG™ Respiratory Pathogen Panel (RUO) lets laboratories simultaneously detect 22 respiratory pathogens in closed tube system. Functionality minimizes required hands-on time and eliminates upstream reagent preparation requirements. Total turnaround time is ~3 hr for 96 samples (excluding extraction), and accompanying SYNCT™ Software provides data analysis and reporting.

Tags: simultaneously respiratory assay detects

 
 

Potassium Ion Channel Assay Kit eliminates wash steps.

2015-02-13 14:30:21| Industrial Newsroom - All News for Today

Optimizing assay window width via thallium-sensitive indicator dye and masking agent, FLIPR® Potassium Assay Kit can be used measure ligand- and voltage-gated potassium channel activity – even those with low conductance or low expression levels. Proprietary masking agent reduces background fluorescence and enhances SNR, while no-wash format simplifies automation using 96-, 384-, and 1,536-well formats in FLIPR and FlexStation microplate readers.

Tags: channel steps kit ion

 

Viral Load Assay supports diagnosis and treatment monitoring.

2014-12-09 14:30:52| Industrial Newsroom - All News for Today

Designed for use on Panther system, Aptima HIV-1 Quant Dx Assay employs proprietary real-time transcription-mediated amplification technology for HIV diagnosis and treatment monitoring. CE mark certified assay uses dual target approach against highly conserved regions in HIV genome, sophisticated primer design, and redundancy of oligonucleotides for protection against mutations, helping to ensure accurate detection and quantitation of HIV-1.

Tags: treatment supports load monitoring

 

Imaging And Analysis Of A High Density Cell Migration Assay

2014-11-25 16:04:37| drugdiscoveryonline Downloads

Complex biological or environmental signaling events can lead to cell migration, the movement of cells from one location to another. The migration of cells commonly occurs during both normal biological processes such as the development of an organism or marking pathological events such as cancer metastasis. Automated processes in higher density formats improve throughput greatly increasing the usefulness of performing migration assays at a larger scale. This study evaluated the use of a high density cell exclusion assay in 384- well format for investigation of cell migration using a cell line stably expressing green fluorescent protein (GFP).

Tags: high analysis cell density

 

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