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Merck Announces Results from Phase 2 Study of Investigational Chronic Hepatitis C Treatment Grazoprevir/Elbasvir in Genotype 1 Infected Treatment-Nave and Difficult-to-Cure Patients

2014-11-11 14:00:00| Merck.com - Research & Development News

Dateline City: BOSTON Final Results from the C-WORTHy Study (Parts A and B) Presented at The Liver Meeting and Published in The Lancet First Wave of Phase 3 Development Program for Grazoprevir/Elbasvir is Fully Enrolled; Merck Plans to Submit New Drug Application in 2015 BOSTON--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced the presentation of results from a multi-arm Phase 2 clinical trial evaluating grazoprevir/elbasvir (MK-5172/MK-8742, the companys investigational NS3/4A protease inhibitor and NS5A inhibitor, respectively) with or without ribavirin (RBV) in treatment-nave and previously-treated (with peg-interferon/ribavirin [PR]) patients with chronic hepatitis C virus (HCV) genotype 1 (GT1) infection -- the C-WORTHy study (Parts A and B). Language: English Contact: MerckMedia:Pam Eisele, 267-305-3558Sarra Herzog, 201-669-6570orInvestors:Joe Romanelli, 908-423-5185Justin Holko, 908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more

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Ironwood Pharmaceuticals Initiates Phase III Trial Of 72 mcg Linaclotide In Adult Patients With Chronic Idiopathic Constipation

2014-11-05 05:57:43| drugdiscoveryonline Home Page

Ironwood Pharmaceuticals, Inc. announced recently the initiation of a Phase III clinical trial in the U.S. evaluating a 72 mcg capsule of linaclotide to be taken once per day for the treatment of adults suffering from chronic idiopathic constipation (CIC)

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Floods Will Be Chronic Problem for East Coast Cities by 2030, Study Says

2014-10-08 20:02:00| Climate Ark Climate Change & Global Warming Newsfeed

Yale Environment 360: By 2030, residents of Washington, D.C., and Annapolis, Maryland, could be experiencing more than 150 tidal floods every year -- up from an average of just 50 today -- according to a recent study of sea level rise and coastal flood risk along the U.S. East Coast by the Union of Concerned Scientists. In another 15 years, that number could jump to 400 floods annually, the study says. A home purchased in some of the more flood-prone parts of those two cities could see daily flooding before a 30-year...

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US tidal floods will be 'chronic' in 15 yrs, study claims

2014-10-08 07:57:00| Climate Ark Climate Change & Global Warming Newsfeed

Agence France-Presse: Many US coastal communities already struggle with flooding at high tides, a problem that will become "chronic" in the coming 15 years due to global warming, scientists said Wednesday. As shorelines are growing more populated, sea levels are swelling due to melting glaciers and polar ice sheets, putting more populations at risk, said a report by the Union of Concerned Scientists. Particularly dire consequences are expected along the US east coast and the Gulf Coast, the report warned. "Our...

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CDC funds of $1m aimed at chronic disease in W.Va.

2014-09-28 01:33:44| Biotech - Topix.net

The Centers for Disease Control and Prevention has awarded grants totaling more than $1 million to support local programs to reduce the incidence of obesity, heart disease, diabetes and stroke in West Virginia. The state has been awarded nearly $600,000, while West Virginia University will receive $427,000.

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