Temporal lobe epilepsy (TLE) is the most common form of seizure activity in humans. It tends to arise predictably in discrete regions on the extreme poles of either side of the brain. The ability to detect signs that a seizure is about to occur, and short-circuit any undesirable neuronal activity with fiber-delivered laser light is arguably the advanced technology we can imagine for our day. It is here -- at least for genetically enhanced Mus musculus, the ordinary house mouse.