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Drug Candidate Shrinks Tumor When Delivered By Plant Virus Nanoparticle
2016-06-09 08:20:34| drugdiscoveryonline News Articles
In a pair of firsts, researchers at Case Western Reserve University and Massachusetts Institute of Technology have shown that the drug candidate phenanthriplatin can be more effective than an approved drug in vivo, and that a plant-virus-based carrier successfully delivers a drug in vivo.
Tags: drug
delivered
plant
candidate
Streamlinging Pharm Drug Development: Yes, It's Time.
2016-06-01 14:14:49| drugdiscoveryonline Downloads
“We’ve always known that working with multiple CMOs is inefficient — there are handoff issues and no incentive for vendors to work together to speed the process. An integrated CDMO could eliminate many steps and save time by parallel processing other steps. Reducing time to milestone is a top priority for us — this would be highly valuable.” — Small pharma CEO1 The path from molecule to market isn’t getting any easier. The costs of drug development continue to rise. Dramatically. According to a 2015 report by Deloitte, costs have increased by a third in just the last five years2. If that weren’t trouble enough, sales during the same time frame have tumbled 50%3. Increased expenditure and decreased income are a bad combination — especially in an industry where the average cost to bring a new product to market approaches $2.6 billion4. It also helps explain why the ROI on R&D is also down 50%5. Obviously, these numbers are not sustainable in the long run. A fundamental change needs to be made, and soon. But this isn’t news. Nobody in the pharmaceutical industry is unaware of these trends — or their underlying meaning. So what’s the solution?
Tags: time
development
drug
pharm
Streamlining Pharm Drug Development: Yes, It's Time.
2016-06-01 14:14:49| drugdiscoveryonline Downloads
“We’ve always known that working with multiple CMOs is inefficient — there are handoff issues and no incentive for vendors to work together to speed the process. An integrated CDMO could eliminate many steps and save time by parallel processing other steps. Reducing time to milestone is a top priority for us — this would be highly valuable.” — Small pharma CEO1 The path from molecule to market isn’t getting any easier. The costs of drug development continue to rise. Dramatically. According to a 2015 report by Deloitte, costs have increased by a third in just the last five years2. If that weren’t trouble enough, sales during the same time frame have tumbled 50%3. Increased expenditure and decreased income are a bad combination — especially in an industry where the average cost to bring a new product to market approaches $2.6 billion4. It also helps explain why the ROI on R&D is also down 50%5. Obviously, these numbers are not sustainable in the long run. A fundamental change needs to be made, and soon. But this isn’t news. Nobody in the pharmaceutical industry is unaware of these trends — or their underlying meaning. So what’s the solution?
Tags: time
development
drug
pharm
H3 Biomedicine Receives FDA Acceptance For Investigational New Drug Application
2016-06-01 06:06:14| drugdiscoveryonline Home Page
H3 Biomedicine Inc., a biopharmaceutical company specializing in the discovery and development of precision medicines for oncology and a member of the Eisai Group, announced recently that the U.S. Food and Drug Administration (FDA) accepted the company’s Investigational New Drug (IND) application to begin Phase 1 clinical trials for its lead oncology drug candidate H3B-8800
Tags: application
drug
acceptance
receives
Evotec Extends Integrated Drug Discovery Alliance with Genentech
2016-06-01 05:49:55| drugdiscoveryonline Home Page
Evotec AG recently announced that Genentech, a member of the Roche Group, has extended its integrated drug discovery alliance with Evotec for a further three years to discover novel small molecule therapeutics
Tags: drug
integrated
discovery
alliance
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