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Cytokinetics, Amgen drug shows promise in heart failure study

2015-11-09 05:29:58| Biotech - Topix.net

ORLANDO: An experimental heart failure drug being developed by Cytokinetics Inc and Amgen Inc demonstrated several beneficial cardiac function effects in a midstage clinical trial, according to data presented on Sunday. The trial of 448 patients with chronic heart failure already receiving optimal care tested a twice-a-day oral version of the drug, omecamtiv mecarbil, against a placebo over 20 weeks.

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Novo Nordisk diabetes drug fails to help heart failure: study

2015-11-09 01:18:18| Biotech - Topix.net

ORLANDO: The Novo Nordisk diabetes drug Victoza failed to improve clinical stability or delay death in patients suffering from advanced heart failure, researchers reported at a medical meeting on Sunday. The injectable drug, known chemically as liraglutide, was tested in 300 patients with and without type 2 diabetes who had advanced heart failure and a recent hospitalization.

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FDA Panel Backs Merck & Co Drug To Reverse Muscle Relaxant Effect

2015-11-07 20:15:36| Biotech - Topix.net

Merck & Co's drug to reverse the effects of muscle relaxants used in surgery is safe and effective enough to warrant approval, an independent panel to the U.S. Food and Drug Administration said. The drug, which goes by the chemical name of sugammadex, has repeatedly been rejected by the FDA due to concerns about potentially dangerous allergic reactions, even though it is approved in more than 75 countries.

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Merck faces probe into asthma drug pricing

2015-11-06 23:06:05| Biotech - Topix.net

Merck & Co. Inc.'s stock dropped 1.5% in midday trade Friday, after the drug maker disclosed in a filing late Thursday that it had received a civil investigative demand from the U.S. Attorney's office.

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Drug makers investigated over pricing

2015-11-06 21:01:30| BBC News | Business | UK Edition

US drug makers Merck and Eli Lilly are being investigated over their pricing policies.

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