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Scancell: Update On Phase 1/2 Clinical Trial Of SCIB1 In Stage III/IV Melanoma

2014-06-03 09:27:50| Logistics - Topix.net

The updated data was presented in a poster at the 2014 American Society of Clinical Oncology meeting in Chicago on Sunday 1 June 2014.

Tags: update stage trial phase

 

Data on Mercks Pembrolizumab from Largest Study to Date of Investigational Anti-PD-1 Antibody in Advanced Melanoma Highlighted at ASCO 2014

2014-06-02 13:30:00| Merck.com - Corporate News

Dateline City: CHICAGO Pembrolizumab as Monotherapy Shows Estimated Overall Survival Rate of 69 Percent at One Year Across 411 Advanced Melanoma Patients with Varying Stages of Disease and Prior Therapy Durable Responses and Consistent Tolerability Profile Observed Across Doses, Including Patients With or Without Prior Ipilimumab Therapy Phase 3 Trials Ongoing or Planned Across Lines of Therapy, Including Adjuvant Treatment CHICAGO--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced new data from the companys large ongoing Phase 1b study (KEYNOTE-001) evaluating pembrolizumab (MK-3475), Mercks investigational anti-PD-1 antibody, as a single agent (monotherapy) in 411 patients with advanced melanoma. Language: English Contact: MerckMedia:Ian McConnell, 973-901-5722orClaire Mulhearn, 908-423-7425orInvestors:Carol Ferguson, 908-423-4465orJustin Holko, 908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more

Tags: date data advanced study

 
 

Merck Announces FDA Acceptance for Review of MK-3475 Biologics License Application for Advanced Melanoma

2014-05-06 14:40:00| Merck.com - Corporate News

Dateline City: BOSTON Priority Review Designation for MK-3475 BLA for Proposed Indication of Unresectable or Metastatic Melanoma in Patients Who Have Been Previously Treated with Ipilimumab Advancing New Phase 3 Studies with MK-3475 in Adjuvant Melanoma, Previously-Untreated Non-Small Cell Lung Cancer, Advanced Head & Neck and Bladder Cancers Data from Studies in Three Different Cancer Types to be presented at 2014 ASCO Annual Meeting Initiating Phase 1 Study with Investigational Anti-GITR Antibody (MK-4166) BOSTON--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the Biologics License Application (BLA) for MK-3475, Mercks investigational anti-PD-1 antibody, for the treatment of unresectable or metastatic melanoma in patients who have been previously treated with ipilimumab. Language: English Contact: MerckMedia:Ian McConnell, 973-901-5722Claire Mulhearn, 908-423-7425orInvestors:Carol Ferguson, 908-423-4465Justin Holko, 908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more

Tags: advanced review application license

 

Drug Firms Focus on Advanced Melanoma

2014-03-24 06:13:41| Biotech - Topix.net

Major pharmaceutical companies are racing to launch breakthrough drugs in the next 18 months to treat advanced melanoma, the deadliest form of skin cancer.

Tags: advanced focus drug firms

 

Amgen vaccine triggers immune response in advanced melanoma -study

2014-03-15 09:04:30| Biotech - Topix.net

An experimental Amgen Inc cancer vaccine used to treat advanced melanoma, the deadliest form of skin cancer, proved effective in a late-stage study in shrinking tumors in a way that suggests the drug triggered the intended systemic immune response, according to data presented on Friday.

Tags: advanced study response immune

 

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