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The Role Of Swine As Preclinical Models For Cardiovascular Disease
2015-03-09 11:59:54| drugdiscoveryonline Home Page
By Mark Johnson, M.S. Senior Director of Surgery Classically, pharma, biotech, and device researchers have relied on rodent models to discover and validate disease targets and mechanisms, as well as for the preclinical development of therapeutics. However, the biology of rodents often fails to accurately predict outcomes in patients – perhaps not surprisingly, as mice are not simply miniature people, but have differences in immune function, lifespan, hematological function, regenerative capacity, and environment (sterile and controlled versus complex and dirty). This lack of translational validity has contributed, in part, to the high failure rate for drug development, particularly in the expensive clinical stage. The use of models in larger animals can help address some of these differences between rodents and human, particularly in cardiovascular disease.
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models
disease
cardiovascular
Pakistan: Women have role in fighting climate change: minister
2015-03-08 12:47:00| Climate Ark Climate Change & Global Warming Newsfeed
Pakistan Today: Federal Minister for Climate Change Mushahid Ullah Khan said on Sunday that women who constitute the majority of the worlds poor are among the most vulnerable to the detrimental impacts of climate change, particularly in developing countries including Pakistan. Yet, they are also vital to solutions to the impacts. He expressed these views in his statement issued from Islamabad on Sunday in context of the International Womens Day 2015. The womens day is celebrated on March 8 every year. This...
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women
role
minister
Jack Wolfskin appoints Mau to CFO role
2015-03-06 10:40:00| Daily apparel & textile news and comment - from just-style.com
German outdoor clothing specialist Jack Wolfskin has appointed Axel Mau to the role of finance chief.
Under Armour moves COO to footwear innovation role
2015-03-05 13:49:00| Daily apparel & textile news and comment - from just-style.com
Performance apparel, shoe and accessories brand Under Armour has unveiled a series of changes to its management team, one of which involves moving COO Kip Fulks to president of footwear and innovation.
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moves
innovation
footwear
Data Loggers Role in the Food Safety Act of 2015
2015-03-05 11:31:17| Industrial Newsroom - All News for Today
In late January 2015, a new bill was introduced to congress concerning food safety and the governing of the topic. The proposed act, known as the Safe Food Act of 2015, would create one independent federal agency for all aspects of food production. Currently, as many as 15 agencies have certain governing power over...
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