For tackling the bioavailability challenges of BCS (Biopharmaceutical Classification System) class II and IV compounds, proven formulation development, analytical and manufacturing capabilities are available at Patheon’s facilities. A variety of approaches are often needed to improve the bioavailability of low solubility BCS class II and IV compounds. Patheon’s Pharmaceutical Development Services combines biopharmaceutics knowledge, preformulation data, and manufacturing technologies with statistical Design of Experiments to overcome bioavailability challenges.