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Merck Announces Positive Study Investigating the Use of KEYTRUDA (pembrolizumab) Compared to Chemotherapy in Patients with Ipilimumab-Refractory Advanced Melanoma

2014-11-16 10:25:00| Merck.com - Research & Development News

Dateline City: ZURICH KEYTRUDA Demonstrated Superiority to Chemotherapy for Primary Endpoint of Progression-Free Survival Findings Presented for First Time at Society of Melanoma Research (SMR) 2014 International Congress ZURICH--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, announced today that a pre-specified analysis of investigational data from a pivotal Phase 2 study (KEYNOTE-002) showed KEYTRUDA (pembrolizumab), the companys anti-PD-1 therapy, substantially improved the primary endpoint of progression-free survival (PFS, as assessed by RECIST 1.1, independent central review) (HR 0.57 and 0.50 for 2 mg/kg and 10 mg/kg every three week doses, respectively), compared to chemotherapy (P<0.0001 for both comparisons) Language: English Contact: MerckMedia:Lainie Keller, 908-236-5036Claire Mulhearn, 908-236-1118orInvestor:Joseph Romanelli, 908-423-5185Justin Holko, 908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more

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Q&A: What exactly is Obama signalling he wants to do with his Net Neutrality support?

2014-11-16 00:57:02| Telecom - Topix.net

Activist Kyle MacDonald of @YesFreeTaxi is offering free rides via twitter request. Kyle explains to the Vancouver Sun why he is giving strangers free car rides in a rooster costume.

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Eaton Corp. computer contractor indicted on federal charges of infecting network with malware

2014-11-15 19:17:36| Industrial Machines - Topix.net

A former contract employee at Eaton Corp. was charged in a federal indictment unsealed Friday with infecting the company's computers with malicious software. Arturas Samoilovas, 35, of Stow, is charged with transmitting and attempting to transmit computer codes, programs or commands, intending to cause damage to a protected computer.

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IEA says oil supplies may not keep up with demand

2014-11-15 17:55:35| Green Car Congress

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How to Get Away With Sleazy Sex Scenes

2014-11-14 08:18:49| Telecom - Topix.net

While Obama's Federal Communications Commission obsesses over liberal concerns like the under-regulation of the Internet and whether "Redskins" is a profanity, broadcast television is sleazier than ever. As The Hollywood Reporter recently noted, "Nearly two months into the fall, it's clear that explicit jokes and boundary-pushing storylines are changing the definition of what sexual content is acceptable in primetime."

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