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Merck KGaA, Darmstadt, Germany, And Pfizer Announce FDA Orphan Drug Designation For Investigational Immunotherapy Avelumab In Merkel Cell Carcinoma
2015-09-30 08:25:02| drugdiscoveryonline News Articles
Merck KGaA, Darmstadt, Germany, and Pfizer recently announced that the US Food and Drug Administration (FDA) has granted orphan drug designation for the investigational cancer immunotherapy avelumab* for the treatment of Merkel cell carcinoma (MCC), a rare and aggressive type of skin cancer
Tags: germany
cell
drug
announce
Quality Assessment Engineering Support in Darmstadt Germany
2015-04-22 18:04:56| Space-careers.com Jobs RSS
POSITION ID 2433 Role Function Image Quality Assessment Engineering Support in Darmstadt Germany GENERAL CONDITIONS START 01 October 2015 PERIOD 2 years 2 options for extension, each option stands for 1 year LOCATION Darmstadt TYPE OF BUSINESS Science CONTRACT fulltime employment WORKING LANGUAGE English, French is considered an advantage DEADLINE 08 June 2015 MUSTHAVE SKILLS MANDATORY In addition to having a University degree or equivalent in a relevant discipline, the Key person shall have Good theoretical knowledge of satellite imagery data processing algorithms for navigation, registration and calibration and techniques used for assessing the geometric and radiometric quality of level 1 image products A minimum of 3 years experience in the processing and analysis of data from imaging andor sounding instruments on remote sensing spacecraft. Significant experience of validating remote sensing products and complex remote sensing data processing systems. In addition, the Key person shall have practical, demonstrable experience inwith Software engineering, in particular in algorithm software development, in a Unix environment using CC, and ideally also Python and MatlabIDL Implementation of scientific algorithms from a given specification. NICETOHAVE SKILLS CONSIDERED AS AN ADVANTAGE Furthermore, it would be a distinct advantage for the knowledge of some of the following Working with relational database preferable Oracle or Postgres Spacecraft andor ground segment operations Imaging and sounding instrumentation for remote sensing spacecraft The key person shall be able to conduct all activities in an orderly and disciplines manner, shall be able to work calmly and correctly under stress and must be able to work with the minimum of supervision. TASKS The tasks of the Key person will typically include Monitoring the mediumterm to longterm performance of Level 1 data processing systems, including the performance of their algorithms, and monitoring the quality of the generated Level 1image products Developing and maintaining image quality assessment software, including the specification, verification and validation testing of software developments Supporting the further development of the Level 1 data processing systems, including the specification, verification and validation testing of system updates and related Level 1 products Supporting the investigation and correction of anomalies related to the performance of the MSGMTP Level 1 data processing systems Supporting the preparations for future GEO and LEO missions in the area of image quality assessment Attendance at technical meetings Participation in formal reviews.
Tags: support
quality
germany
engineering
MHS and NOAA Instruments Engineering Support in Darmstadt Germany
2015-04-22 18:04:56| Space-careers.com Jobs RSS
POSITION ID 2435 Role Function MHS and NOAA Instruments Engineering Support in Darmstadt Germany GENERAL CONDITIONS START ASAP PERIOD 3 years 2 options for extension, each option stands for 1 year LOCATION Darmstadt TYPE OF BUSINESS Science CONTRACT fulltime employment WORKING LANGUAGE English, French is considered an advantage DEADLINE 03 June 2015 MUSTHAVE SKILLS MANDATORY The Key person is required to have the experience and capability to fulfil the assigned tasks with the minimum of supervision and minimum training. The Key person shall have a university degree in engineering or physics and, as a prerequisite, a background of at least 5 years in space hardware projects possibly with Earth observation instruments. Experience in project management positions is desirable together with the ability to follow satellite level Payload AIV activities. The Key person shall also have some knowledge of PAQA processes and procedures and good general computing skills, with familiarity with Microsoft Office software Excel, Word, PowerPoint, etc.. Previous experience in AIVAIT and commissioning activities is regarded as advantageous along with experience of working on a collaborative programme between different partners. The working language for the position is English and therefore the Key person must be able to work effectively in this language and have some knowledge of the other. TASKS Support to Microwave Humidity Sounder MHS and National Oceanic and Atmospheric Administration NOAA Instruments Engineering Activities. The tasks of the MHS and NOAA Instruments Engineer shall include the following Participation to Metop satellite AIV, Launch and Commissioning activities relevant to the MHS and NOAA instruments, including operation of the MHS EGSE, data analysis, preparation of procedures and test reports instrument ground testing at sc level, endtoend testing at system level, satellite inorbit verification. Maintenance of an uptodate plan of Metop satellite AIV, Launch and Commissioning activities requiring support for the MHS and the NOAA instruments. Follow up all activities related to MHS carried out by the Airbus DSUK and maintain a list of PDS activities and their status and expenditures. Follow up of all activities related to the NOAA instruments including AVHRR and SEM instruments onground calibration. Support inorbit checkout verification tests during MetopC In Orbit Verification IOV. Investigation of onground and inorbit instrument anomalies and support operations to the relevant recovery actions. Provide general support to the Metop Operations Team for MHS and NOAA instruments matters. Analyse and assess both onground and inorbit performances of MHS and NOAA instruments. Participation to instrument reviews and other meetings with industry and other partnerssuch as ESA, NOAANASA. Maintenance of regular contacts with the above mentioned EUMETSAT partners and industry in relation to MHS and NOAA instruments. Maintenance of a status list of MHS action items, nonconformancesanomalies, requests for waivers and deviations. Preparation and maintenance of instrument related documents, as well as presentation material e.g. Instrument Operational Manuals
Tags: support
germany
instruments
engineering
Spacecraft Operations Engineer at ESAESOC in Darmstadt
2015-04-22 13:04:04| Space-careers.com Jobs RSS
Vitrociset Belgium is looking for a candidate with the profuile described below to deploy in ESOC in the domain of Spacecraft Operations Engineering. The engineer will be required to support spacecraft operations as a member of a Flight Control Team. TASKS The main tasks of a Spacecraft Operations Engineer are as follows Mission preparation, LEOP and commissioning phases Review mission documentation and define spacecraft operations concept, based on the missions objectives. Follow the development of the spacecraft and interface with project group and industry for technical matters and review of spacecraft design, interfaces to the ground segment and operations documentation. Review of the existing infrastructure and mission systems to define system and subsystem requirements for the mission. Support the definition, preparation and execution of ground segment validation tests. of the procedures for nominal and contingency cases. Support the preparation of additional operational products such as Flight Operations Plan, Operations Reports and Database. Support the preparation and execution of the System Validation Tests SVT. Support the preparation and execution of the simulations campaigns. Support the preparation and execution of the operations including prelaunch, LEOP and commissioning phases. Identify, record, and support the investigation and progression of spacecraft and groundbased anomalies during the SVTs, simulations campaign and LEOP. Mission routine phase Support the planning and execution of spacecraft routine operations, both online and offline. Support the execution of routine and contingency operations as required. Support the planning and execution of special operations. Support the analysis of spacecraft and ground segment performance. Perform systems and payload monitoring and long term trend evaluations. Support anomaly investigations, tracking followup. Support the regular generation of operations reports. Support the maintenance of procedures to take into account spacecraft failures, reconfigurations or new requirements. Provide support for the oncall service. Interface with other internal and external teams. PROFILE Academic requirements a University or similar degree in engineering, physics or similar discipline. Qualifications Good knowledge of spacecraft subsystems. Familiarity with operational environment. Ability to understand complex systems and to derive operational procedures Proactive and confident personality with good persuasive skills. Able to work in an interdisciplinary team. CONTACT INFORMATION Please submit applications not later than 310515 by EMAIL to Mr. Mario Monaldi, Site Manager, M.Monaldivitrocisetbelgium.com cc. jobsvitrocisetbelgium.com
Tags: operations
engineer
darmstadt
spacecraft
Ground Operations Engineer at ESAESOC in Darmstadt
2015-04-22 13:04:04| Space-careers.com Jobs RSS
Vitrociset belgium is looking for a candidate with the profile described below to deploy in ESOC in the domain of Ground Operations Engineering. Ground Operations Engineers are responsible for providing the ops engineering required for their missions during preparation and execution phase. During the routine phase they are the first level of escalation above ECC and Scheduling Office. TASKS The tasks to be carried out by the Ground Operations Engineer are Participate in the mission specific validation of ground segment elements prior to critical operations. Participate, when nominated, as OM in the critical operations phases for that mission. Participate in the definition of mission specific ground station configuration in the ops preparation phase and after major modifications. Participate in the validation of station configuration and MC tailoring for remote operations. Define and give mission specific training to ECC staff during lifetime of mission. Participate in the certification of operators. Generate and maintain mission specific Ground Operations documentation e.g. GOP, training material during lifetime of mission. Monitor performance of ESTRACK services provided to customers and trigger corrective actions in case of degradations. Initiate or conduct investigations into anomalies affecting the Ground service to the mission. Participate in regular meeting with missions e.g. WORM, ICM or event driven meetings e.g. MRBs. In addition to these mission and service dedicated tasks, GOEs may be charged with specific facility or tools orientated duties. Latter are typically related to the definition, development and validation of new technical systems for ESTRACK operations. PROFILE Academic Requirements Bachelor or higher degree in a technical field related to ground stations operations. Specific Requirements Candidates should have several years of experience in operating ground station networks. As a preference they should have a thorough understanding of the technical systems related to ESTRACK and partner networks and be familiar with the ESOC working environment. Knowledge or experience in mission operations, i.e. the ESTRACK customer side, would be an asset. The proven ability of candidates to work independently in a technically complex and multinational environment is a prerequisite. CONTACT INFORMATION Please submit applications not later than 310515 by EMAIL to Mr. Mario Monaldi, Site Manager, M.Monaldivitrocisetbelgium.com cc. jobsvitrocisetbelgium.com
Tags: ground
operations
engineer
darmstadt